The predictive value of CSF multiple assay in multiple sclerosis: A single center experience.

C De Fino,M Lucchini,D Lucchetti,V Nociti,F A Losavio,A Bianco,F Colella, C Ricciardi-Tenore,A Sgambato,M Mirabella

Multiple Sclerosis and Related Disorders（2019）

引用 15|浏览18

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摘要

•Multiplex assay allows a multiple biomarker analysis with a small CSF sample.•CSF CD163 and CHI3L1 baseline level are higher in MS patients than in controls.•In CIS, higher CSF CHI3L1 and CD163 levels are associated with conversion to MS.•CSF BAFF levels are lower in OCB+ possibly for higher consumption by B cells.

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关键词

Multiple Sclerosis,CHI3L1,sCD163,Osteopontin,BAFF

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