Hedgehog signaling promotes TH2 differentiation in naive human CD4 T cells.

Diana C Yánez,Ching-In Lau,Mira Manilal Chawda,Susan Ross,Anna L Furmanski,Tessa Crompton

The Journal of allergy and clinical immunology（2019）

引用 17|浏览26

暂无评分

摘要

Here we show that differentiation of human naïve CD4 T-cells to Th2 is promoted by Hedgehog signaling and attenuated by SMO-inhibition. As Hedgehog proteins are produced by epithelial tissues this finding is important to understanding atopic disease.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要