Assessment of a New ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in Non-Small Cell Lung Carcinoma Patients: the ROSING Study.

Esther Conde,Susana Hernandez,Rebeca Martinez,Barbara Angulo,Javier De Castro,Ana Collazo-Lorduy,Beatriz Jimenez,Alfonso Muriel,Jose Luis Mate,Teresa Moran,Ignacio Aranda,Bartomeu Massuti,Federico Rojo,Manuel Domine,Irene Sansano,Felip Garcia,Enriqueta Felip,Nuria Mancheño,Oscar Juan,Julian Sanz,Jose Luis Gonzalez-Larriba,Lidia Atienza-Cuevas,Esperanza Arriola-Arellano,Ihab Abdulkader,Jorge Garcia-Gonzalez,Carmen Camacho,Delvys Rodriguez-Abreu,Cristina Teixido,Noemi Reguart,Ana Gonzalez-Piñeiro,Martin Lazaro-Quintela,Maria Dolores Lozano,Alfonso Gurpide,Javier Gomez-Roman,Marta Lopez-Brea,Lara Pijuan,Marta Salido,Edurne Arriola,Amparo Company,Amelia Insa,Isabel Esteban-Rodriguez,Monica Saiz,Eider Azkona,Ramiro Alvarez,Angel Artal,Maria Luz Plaza,David Aguiar,Ana Belen Enguita,Amparo Benito,Luis Paz-Ares,Pilar Garrido,Fernando Lopez-Rios

Journal of Thoracic Oncology（2019）

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摘要

The new SP384 ROS1 IHC clone showed excellent sensitivity without compromising specificity, so it is another excellent analytical option for the proposed testing algorithm.

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关键词

ROS1,Immunohistochemistry,FISH,Next-generation sequencing,Lung carcinoma

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