Striatal morphology and neurocognitive dysfunction in Huntington disease: The IMAGE-HD study.
Psychiatry Research: Neuroimaging(2019)
摘要
•Neostriatal shape differences were detected between controls, pre-HD, and symp-HD.•These shape changes were associated with measures of disease burden.•Neostriatal shape changes also correlated with motor and neurocognitive measures.
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关键词
Neostriatum,Endophenotype,Biomarker Huntington disease
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