The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma

Dongbing Liu
Dongbing Liu
Shuzhen Luo
Shuzhen Luo
Sha Fu
Sha Fu
Xuan Wu
Xuan Wu
Huaqiang Zhou
Huaqiang Zhou
Xi Chen
Xi Chen
Zhonghan Zhang
Zhonghan Zhang

Nature communications, Volume 10, Issue 1, 2019, Pages 3108

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Abstract:

Pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare and distinct subtype of primary lung cancer characterized by Epstein-Barr virus (EBV) infection. Herein, we reported the mutational landscape of pulmonary LELC using whole-exome sequencing, targeted deep sequencing and single-nucleotide polymorphism arrays. We identify a low degr...More

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