The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma

    Dongbing Liu
    Dongbing Liu
    Shuzhen Luo
    Shuzhen Luo
    Sha Fu
    Sha Fu
    Xuan Wu
    Xuan Wu
    Huaqiang Zhou
    Huaqiang Zhou
    Zhonghan Zhang
    Zhonghan Zhang

    Nature communications, Volume 10, Issue 1, 2019, Pages 3108

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    Abstract:

    Pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare and distinct subtype of primary lung cancer characterized by Epstein-Barr virus (EBV) infection. Herein, we reported the mutational landscape of pulmonary LELC using whole-exome sequencing, targeted deep sequencing and single-nucleotide polymorphism arrays. We identify a low degr...More

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