High iodine induces DNA damage in autoimmune thyroiditis partially by inhibiting the DNA repair protein MTH1.

Fuqiang Li,Yijun Wu,Liang Chen,Liang Hu,Feng Zhu,Qiwen He

Cellular Immunology（2019）

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摘要

•HI treatment induces DNA damage in autoimmune thyroiditis.•HI treatment decreases MTH1 expression.•MTH1 overexpression reverses the HI-induced DNA damage.

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关键词

Iodine,DNA damage,Apoptosis,Inflammation,MTH1

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