Bed Nets, Insecticides, and Antimalarials: Where to Next?

Insecticide-impregnated bed nets have saved millions from fatal malaria, but their effectiveness is waning due to mosquito insecticide resistance. A new strategy (Paton et al, Nature, 2019) to deliver parasiticidal compounds into mosquitoes to kill transmission stage parasites could enhance the effectiveness of bed nets and get around the perennial problems of resistance.