E2F6-mediated lncRNA CASC2 down-regulation predicts poor prognosis and promotes progression in gastric carcinoma.

Yingxia Li,Libin Jiang,Shuai Lv, Haiyan Xu,Zhoupei Fan,Yixin He,Hongtao Wen

Life Sciences（2019）

引用 23|浏览4

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摘要

Our data demonstrated that E2F6 could regulate the proliferation, invasion and apoptosis of GC cells via inhibiting the expression of CASC2, suggesting that E2F6/CASC2 axis is another regulator of GC progression.

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关键词

Gastric carcinoma,Transcription factor E2F6,Cancer susceptibility candidate 2,Proliferation,Tumorigenesis

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