Dataset On Structure, Stability And Myocardial Effects Of A New Hybrid Aspirin Containing Nitrogen Monoxide-Releasing Molsidomine Moiety

DATA IN BRIEF(2019)

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摘要
Herein H-1 and C-13 NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the linsidomine-aspirin hybrid in oxidation reactions. This data article also concerns miscellaneous myocardial parameters of isolated rat hearts as a complementation of the tables shown in the paper entitled "A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety" Szoke et al., 2019. Column tables represent data of aorta flow, aortic pressure, derivated aortic pressure and cardiac output. (c) 2019 The Authors. Published by Elsevier Inc.
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关键词
ERJ-500, Hybrid aspirin, Molsidomine
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