Edoxaban Versus Warfarin in Patients With Atrial Fibrillation and History of Liver Disease.

Arman Qamar,Elliott M Antman,Christian T Ruff,Francesco Nordio,Sabina A Murphy,Laura T Grip,Norton J Greenberger,Ophelia Q P Yin,Youngsook Choi,Hans J Lanz,Michele F Mercuri,Eugene Braunwald,Robert P Giugliano

Journal of the American College of Cardiology（2019）

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摘要

Among patients with AF receiving oral anticoagulation, bleeding, but not thromboembolic events, was increased in patients with liver disease. A history of liver disease did not alter the relative efficacy and safety of edoxaban compared with warfarin. Hepatic adverse events were similar between edoxaban and warfarin.

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关键词

atrial fibrillation,bleeding,liver disease,stroke

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