Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells

    Raphael Wolfisberg
    Raphael Wolfisberg
    Kenn Holmbeck
    Kenn Holmbeck
    Louise Nielsen
    Louise Nielsen

    Journal of virology, 2019.

    Cited by: 0|Bibtex|Views2|Links
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    Abstract:

    Animal hepaciviruses represent promising surrogate models for hepatitis C virus (HCV), for which there are no efficient immunocompetent animal models. Experimental infection of laboratory rats with rodent hepacivirus isolated from feral (RHV-rn1) mirrors key aspects of HCV infection in humans, including chronicity, hepatitis and steatosi...More

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