The effect of perioperative anesthetics for prevention of postoperative delirium on general anesthesia: A network meta-analysis.

•Question: Which sedative agent is associated with less postoperative delirium and patient-reported adverse events?•Finding: Using a scientific approach, dexmedetomidine use showed reduced postoperative delirium compared to other agents.•Meaning: Dexmedetomidine can be used with regard to reducing postoperative delirium without obvious adverse events.