Polymorphisms involving the Pneumocystis jirovecii-related genes in AIDS patients in eastern China.

Mengyan Wang,Xiaoke Xu,Yongzheng Guo,Ran Tao,Caiqin Hu,Xiaotian Dong,Ying Huang,Biao Zhu

Infection, Genetics and Evolution（2019）

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摘要

•The gene combination of mt85C, CYB1, SOD1, and DHFR312T showing the highest frequency.•The gene combination of mt85T, CYB1, SOD1, and DHFR312T may be associated with poor clinical outcome.•The types of genetic polymorphisms and polymorphic combinations in P. jiroveci were related to the clinical outcomes of patients.

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关键词

Pneumocystis jirovecii,Genotypes,AIDS,SNPs,Mortality

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