Full title: Adipocyte-derived extracellular vesicles modulate appetite and weight through mTOR signaling in the hypothalamus.

Adipocyte-derived extracellular vesicles play important roles in mediating the interaction between adipocytes and hypothalamic neurons. Adipocyte-derived extracellular vesicles can regulate POMC expression through the hypothalamic mTOR signaling in vivo and in vitro, thereby affecting body energy intake. This article is protected by copyright. All rights reserved.