Immunohistochemistry in the workup of bladder biopsies: Frequency, variation and utility of use at an academic center.

Patrick McIntire,Reema Khan,Irem Kilic,Eva M Wojcik,Stefan E Pambuccian,Güliz A Barkan

Annals of Diagnostic Pathology（2019）

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摘要

•Examined the frequency and utility of IHC in bladder biopsies over 17 year period.•There were 345 specimens (7.5%, 399/4252) in which IHC was ordered.•Atypical, dysplastic and carcinoma in-situ rates were similar regardless of IHC use.•IHC orders have drastically fallen off in last 5 years (only 5 cases in 2017).

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关键词

Immunohistochemistry,Carcinoma in-situ,Reactive atypia,Urothelium,Urothelial carcinoma

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