MicroRNA-126-5p downregulates BCAR3 expression to promote cell migration and invasion in endometriosis.

•Upregulation of BCAR3 in eutopic and ectopic endometrium.•BCAR3 overexpression promotes the proliferation, migration, and invasion of ESCs.•BCAR3 is the direct target of miR-126-5p.•Estrogen promoted EMT in the ectopic endometrium of endometriosis.•BCAR3 did not have a synergistic effect on EMT with estrogen.