Inter observer variability among gynecologists in manual cervix image analysis for detection of cervical epithelial abnormalities

Cancer cervix is amenable to screening and early detection. Although Pap smear is the most widely used tool for cervical cancer screening, it has its own drawbacks in terms of low sensitivity (52%)1 and the need for efficient networking between smear collection and cytology laboratories.2 Besides, varying levels of sensitivity and specificity has been reported based on the grade of intraepithelial neoplasia [(sensitivity and specificity of 93%and 73% in low grade intraepithelial neoplasia (LSIL) versus 64% and 84% in high grade intraepithelial neoplasia (HSIL)]3