Electrochemical Detection of Zika Virus in Biological Samples: A Step for Diagnosis Point‐of‐care
ELECTROANALYSIS(2019)
摘要
This work describes an electrochemical genosensor for detection of genomic RNA of Zika virus in real samples of infected patients, using a new platform based on graphite electrodes modified with electrochemically reduced graphene oxide and polytyramine-conducting polymer. The developed genosensor was suitable for differentiation between samples of healthy and infected patients with Zika virus by differential pulse voltammetry, detecting up to 0.1 fg/mL (1.72 copies/mL), showing good stability (about 60 days), rapid analysis (about 20 min) and potential for filling the lack of practical diagnostic methods for Zika virus.
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关键词
genosensor,diagnosis,nanomaterials,polytyramine,Zika virus
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