PO-0983 Accumulating delivered dose to the rectum using finite element analysis improves toxicity prediction

▪ In prostate cancer radiotherapy, the rectum is a dose-limiting organ▪ Delivered dose to the rectal wall in prostate radiotherapy differs from planned dose due to interfraction motion and deformation [1]▪ The hypothesis of the VoxTox research programme [2, 3] is that delivered dose is a better predictor of toxicity than planned dose