Anti-pancreatic-cancer effect of a newly bred cabbage line, Amtak-ssamchae, is mediated by a reduction in regulatory-T-cell recruitment

Sunggun Kim,Soo Jeong Kim,Eun-Sang Jo, Kicheol Gil,Na-Yeon Kim, Ji Sung Park, Dongbok Park,So-Young Park,Kwang Woo Hwang

Journal of Functional Foods（2019）

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摘要

•Antitumor effects of Amtak-ssamchae on pancreatic cancer were investigated.•Amtak-ssamchae is designed to increase the amounts of carotenoids by breeding.•Amtak-ssamchae interfered Treg recruitment leading to inhibiting tumors.•Amtak-ssamchae could be a natural supplement for pancreatic cancer.

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关键词

Amtak-ssamchae,Pancreatic cancer,Regulatory T cell,β-carotene,Chemokine receptor,Chemokine receptor ligand

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