Association of AEBP1 and NRN1 RNA expression with Alzheimer's disease and neurofibrillary tangle density in middle temporal gyrus.

Ignazio S Piras,Jonida Krate,Elaine Delvaux,Jennifer Nolz,Matthew D De Both,Diego F Mastroeni,Geidy E Serrano,Lucia I Sue,Thomas G Beach,Paul D Coleman,Matthew J Huentelman

Brain Research（2019）

引用 16|浏览26

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摘要

•AEBP1 and NRN1 are differentially expressed in AD brain.•AEBP1 and NRN1 are correlated with Braak stage and tangles density.•Non-protein coding RNAs perturb GABAergic and other synaptic pathways.

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关键词

Alzheimer’s disease,RNA sequencing,AEBP1,Braak staging,Neurofibrillary tangles,Non-protein coding RNAs

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