Glucopyranosyl lipid adjuvant enhances immune response to Ebola virus-like particle vaccine in mice.

Melek M E Sunay,Karen A O Martins,Jesse T Steffens,Melissa Gregory,Sean A Vantongeren,Neal Van Hoeven, Preston G Garnes,Sina Bavari

Vaccine（2019）

引用 16|浏览14

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摘要

•GLA-SE combined with EBOV VLP confers lasting protection against ma-EBOV.•GLA-SE inclusion elicits Th1-skewed antibodies.•GLA-SE enhances EBOV-specific polyfunctional T cells.

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关键词

Vaccine,Adjuvant,TLR agonist,Protection,Ebola virus

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