AKAP12 deficiency impairs VEGF-induced endothelial cell migration and sprouting.

Peter M Benz,Yindi Ding,Heike Stingl,Annemarieke E Loot,Joana Zink,Ilka Wittig,Rüdiger Popp,Ingrid Fleming

Acta physiologica (Oxford, England)（2020）

引用 24|浏览16

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摘要

The results suggest that compartmentalized AKAP12/PKA signaling mediates VASP phosphorylation at the leading edge of migrating endothelial cells to translate angiogenic stimuli into altered actin dynamics and cell movement. This article is protected by copyright. All rights reserved.

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关键词

Angiogenesis,Protein kinase A,Protein kinase A anchoring protein 12,Retina,Vasodilator-stimulated phosphoprotein

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