Influence of demographic and clinical features of the patient on transit times and impact the on the diagnostic yield of capsule endoscopy.

Background: transit times in the gastric cavity and the small bowel can be easily calculated using capsule endoscopy software. The factors that can influence these times and impact on diagnostic yield have not been completely assessed. Aims: to analyze the influence of demographic and clinical features on transit times and the impact on diagnostic yield. Methods: a retrospective, single-center study of examinations between January 2013 and November 2017 was performed. The analyzed features included gender, age, body mass index, diabetes, thyroid disease and indications. The association and correlation between the variables were assessed, as well as the presence of positive and significant findings. Results: six hundred and thirty-one patients were included in the study. Gastric and small bowel transit times were 36.10 +/- 48.50 and 251.82 +/- 116.42 minutes, respectively. Gastric time was not affected by any of the variables. Small bowel time was longer in males, patients over 60 years of age and diabetics. Prolonged small bowel time, male gender and older age were associated with a higher diagnostic yield. Age over 60 years was the only factor independently associated with positive findings (OR: 1.550 [1.369-1.7541; p: 0.007). Conclusions: patients over 60 years have a longer small bowel transit time and higher probability of having small bowel lesions. Males and diabetic patients also seem more likely to have longer transit times and higher rates of positive findings.