Multi-Phenotype Association Decomposition: Unraveling Complex Gene-Phenotype Relationships

Frontiers in genetics, Volume 10, 2019, Pages 417

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Keywords:
GWASSNP clusteringhypothesis generationmulti-phenotype associationsnetworksMore(3+)

Abstract:

Various patterns of multi-phenotype associations (MPAs) exist in the results of Genome Wide Association Studies (GWAS) involving different topologies of single nucleotide polymorphism (SNP)-phenotype associations. These can provide interesting information about the different impacts of a gene on closely related phenotypes or disparate phe...More

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