Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a

qinghua liu
qinghua liu
sijie cheng
sijie cheng
lingna zhao
lingna zhao
min xia
min xia
cheng wang
cheng wang
lili zhang
lili zhang

bioRxiv, pp. 623132-47, 2019.

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Keywords:
long noncoding RNA<italic>AVAN</italic>virus immunityFOXO3aTRIM25

Abstract:

Accumulating evidence has shown that long noncoding RNAs (lncRNAs) are involved in several biological processes, including immune responses. However, the role of lncRNAs in antiviral innate immune responses remains largely unexplored. Here, we identify an uncharacterized human lncRNA, antivirus and activate neutrophil (AVAN), that is sign...More

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