Evaluating the Efficacies of Carbapenem/β-Lactamase Inhibitors Against Carbapenem-Resistant Gram-Negative Bacteria in vitro and in vivo .

FRONTIERS IN MICROBIOLOGY(2019)

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摘要
New carbapenem/βLI combinations may be viable alternatives to antimicrobial combination therapy as they displayed high efficacy and Meropenem/Avibactam and Meropenem/Relebactam should be tested on larger sample sizes with different carbapenemases before progressing further in its preclinical development.
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关键词
Avibactam,KPC,NDM-1,OXA-48,Relebactam,antimicrobial resistance,calcium-EDTA,carbapenem
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