Chronic total occlusion or non‐chronic total occlusion percutaneous coronary intervention: Do myocytes really care?

Key Points Chronic total occlusions subtend a more extensive perfusion defect size compared to non-chronic total occlusion lesions. Chronic total occlusion percutaneous coronary intervention (CTO PCI) results in significant improvement in myocardial blood flow and reduction in perfusion defect size. Improvement in hyperemic myocardial blood Flow (MBF), coronary flow reserve (CFR) and perfusion defect size is comparable in CTO and hemodynamically significant non-CTO PCI.