Nickel‐Catalyzed Cascade Annulation for the Rapid Synthesis of Carbocyclic Nitriles

Xianjie Fang,Peng Yu,Suzanne Willems,Bill Morandi

HELVETICA CHIMICA ACTA（2019）

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摘要

We report a Ni-catalyzed cascade annulation reaction that proceeds through two sequential carbometallation steps followed by C-CN reductive elimination. This reaction transforms two simple starting materials into complex, carbocyclic nitriles.

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关键词

nitrile,nickel,alkynes,alkenes,annulation

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