A Comparative Study Of The Antimicrobial And Antioxidant Activities Of Inonotus Hispidus Fruit And Their Mycelia Extracts
INTERNATIONAL JOURNAL OF FOOD PROPERTIES(2019)
摘要
Inonotus hispidus (Bull.) P. Karst. has been used as traditional medicine for the treatment of dyspepsia, cancer, and diabetes. Numerous studies have confirmed the antimicrobial, antiviral, antioxidant, anti-inflammatory, immunomodulatory, antiproliferative and cytotoxic biological activities of extracts from this species. The purpose of this study was a comparative analysis of the antioxidant and the antimicrobial activities of methanol extracts from fruit and liquid-cultured mycelia. Four compounds (N-butylbenzenesulfonamide, lauramidopropyl betaine, 3,5-di-tert-butyl-4-hydroxybenzaldehyde, and uplandicine), determined by hybrid HRMS, were found only in mycelia culture extracts. Free radical scavenging, measured by DPPH assay on methanol extracts, showed an activity of about 17.2% and 22.1% of Trolox in fruiting bodies and mycelia, respectively. The I. hispidus methanol extracts from fruit and mycelia culture were found to have varying degrees of antibacterial and antifungal effects against the pathogenic microorganisms tested (minimum inhibitory concentration from 0.17 to 2.56 mu g mL(-1)).
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关键词
Antibacterial, antifungal, antiradical, N-butylbenzenesulfonamide, lauramidopropyl betaine, uplandicine, 3-di-tert-butyl-4-hydroxybenzaldehyde, biotechnological potential
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