Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India.

Michael H Woodworth,David Dynerman,Emily D Crawford,Sarah B Doernberg, Lynn Ramirez-Avila,Paula Hayakawa Serpa,Amy Nichols,Lucy M Li,Amy Lyden,Cristina M Tato,Steve Miller,Joseph L Derisi,Charles Langelier

bioRxiv（2019）

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摘要

Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India. We identified close phylogenetic relatedness to the South Asia clade and ERG11 Y132F and FKS1 S639Y mutations potentially explaining antifungal resistance.

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关键词

Candida auris,emerging infection,antimicrobial resistance,echinocandin resistance,metagenomic

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