Removal of Cell Wall Polysaccharide in Pneumococcal Capsular Polysaccharides by Selective Degradation via Deamination

Wei Zou,Jianjun Li,Evguenii Vinogradov,Andrew Cox

Carbohydrate Polymers（2019）

引用 4|浏览13

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摘要

•Deamination as a C-polysaccharide degradation method to improve vaccine production.•C-polysaccharide removed from pneumococcal polysaccharides except serotype 1.•Proposed deamination mechanisms for C-polysaccharide and serotype 1 polysaccharide.

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关键词

Pneumococcal capsular polysaccharide,Cell wall polysaccharide,Deamination,Degradation,Mechanism

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