Potent NETosis inducers do not show synergistic effects in vitro .

CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY(2019)

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摘要
Our results show that simultaneous stimulation of neutrophils by different NETosis-inducing agents results in diminished formation of NETs compared to a single stimulation. This indicates that cells may possess an internal regulatory mechanism that prevents overgeneration of NETs among healthy people.
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关键词
NETosis,autoimmunity,neutrophil cross-stimulation,neutrophil extracellular traps
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