Retinal oximetry: Metabolic imaging for diseases of the retina and brain

Einar Stefánsson,Olof Birna Olafsdottir,Thorunn S. Eliasdottir,Wouter Vehmeijer,Anna Bryndis Einarsdottir,Toke Bek,Thomas Lee Torp,Jakob Grauslund,Thor Eysteinsson,Robert Arnar Karlsson,Karel Van Keer,Ingeborg Stalmans,Evelien Vandewalle,Margarita G. Todorova,Martin Hammer,Gerhard Garhöfer,Leopold Schmetterer,Martin Šín,Sveinn Hakon Hardarson

Progress in Retinal and Eye Research（2019）

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摘要

Retinal oximetry imaging of retinal blood vessels measures oxygen saturation of hemoglobin. The imaging technology is non-invasive and reproducible with remarkably low variability on test-retest studies and in healthy cohorts. Pathophysiological principles and novel biomarkers in several retinal diseases have been discovered, as well as possible applications for systemic and brain disease.

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关键词

Retinal oximetry,Retina,Eye,Oxygen,Biomarker,Diabetic retinopathy,Classification,Retinal vein occlusion, retinal ischemia,Glaucoma,Progression of glaucoma,Retinitis pigmentosa,Retinal dystrophy,Retinal atrophy,Alzheimer's disease,Multiple sclerosis,Heart,Cardiac output,Brain,Central circulation

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