An Efficient Synthesis of Angelmarin and its Analogs

Su-You Liu,Na Xu,Li-Jun Liu,Ying-Xiong Wang,Da-You Ma

NATURAL PRODUCT COMMUNICATIONS（2017）

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摘要

Angelmarin, a naturally occurring coumarin, exhibited highly anti-austerity potency towards human pancreatic carcinoma cell line PANC-1. In this paper, an efficient and eco-friendly synthesis of angelmarin and its analogs from columbianetin has been developed via a ZnO mediated esterification and a Wittig reaction.

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关键词

Angelmarin,Analogs,Columbianetin,Synthesis

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