OVERUSE AND LIMITED BENEFIT OF CHEMOTHERAPY FOR STAGE II COLON CANCER IN YOUNG PATIENTS.

The benefit of adjuvant chemotherapy in stage II colon cancer is debated. A retrospective analysis of the National Cancer Database demonstrates more frequent use of chemotherapy in patients with both high- and normal-risk stage II colon cancer who are younger than 50 years compared with older patients. No survival benefit was found to be associated with adjuvant chemotherapy in either risk group.