Race reporting and disparities in clinical trials on Alzheimer’s disease: A systematic review

Marco Canevelli,Giuseppe Bruno,Giulia Grande,Federica Quarata,Riccardo Raganato,Francesca Remiddi,Martina Valletta,Valerio Zaccaria,Nicola Vanacore,Matteo Cesari

Neuroscience & Biobehavioral Reviews（2019）

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摘要

•Race is an important health determinant.•Race is insufficiently considered in research protocols targeting AD.•Race may influence the efficacy and safety profiles of anti-dementia medications.•Blacks and Hispanics are underrepresented in clinical trials on AD.•The collecting and reporting of data on race should be improved.

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关键词

Alzheimer’s disease,Dementia,Race,Randomized controlled trial,External validity,Precision medicine

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