LONG-TERM TREATMENT WITH APIXABAN OF PARTICIPANTS FOLLOWING CONCLUSION OF AVERROES

Alexander Benz,John Eikelboom,Salim Yusuf,Stefan Hohnloser,Heather Beresh, Kumar Ramakrishna,Stuart J. Connolly

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2019）

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摘要

AVERROES, a randomized trial in high-risk patients with atrial fibrillation, unsuitable for vitamin K antagonist therapy, demonstrated the efficacy and safety of apixaban compared to aspirin for stroke prevention. As AVERROES was concluding, the long-term open-label extension (LTOLE) study was

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