Real-Life Experience Of Trastuzumab Use Among 806 Breast Cancer Patients: Role Of Routine Serial Echocardiography For The Evaluation Of Asymptomatic Ventricular Dysfunction In The First 6 Months Of Trastuzumab Therapy

Carolina M.P.D. Carvalho Silva,Marcio Bittencourt,Marilia Santos,Cristina Bittar,Silvia Fonseca, Giovanni Pinto, Isabela Costa, Clara Figueiredo, Julio Siqueira, Marina Bond, Paulo Neto, Thalita Gonzalez,Laura Testa,Paulo Hoff,Roberto Kalil-Filho,Ludhmila Hajjar

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2019）

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摘要

Although serial echocardiography (ECHO) is recommended every three months during treatment with trastuzumab for cardiotoxicity screening, this recommendation is based on expert opinion. We sought to investigate the incidence of Trastuzumab cardiotoxicity in real-world patients, its potential impact

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