Guaraná (Paullinia cupana) catechins and procyanidins: Gastrointestinal/colonic bioaccessibility, Caco-2 cell permeability and the impact of macronutrients

Thaíse Maria Nogueira Mendes, Yukihisa Murayama, Natsumi Yamaguchi,Geni Rodrigues Sampaio,Luciana Cristina Brigatto Fontes,Elizabeth Aparecida Ferraz da Silva Torres,Hirotoshi Tamura,Lina Yonekura

Journal of Functional Foods（2019）

引用 28|浏览12

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摘要

•Guaraná catechin monomers and dimers can permeate across Caco-2 cell monolayers.•Intestinal permeation of guaraná catechins not changed by additional macronutrients.•Oil improves the bioaccessibility of total procyanidins.•A fast and sensitive isocratic HPLC-UV method was developed for guaraná catechins.

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关键词

Caco-2 cells,Catechin,Guaraná,In vitro digestion,Macronutrients,Casein

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