Plaque morphology assessed by optical coherence tomography in the culprit lesions of the first episode of acute myocardial infarction in patients with low low-density lipoprotein cholesterol level.

Taishi Yonetsu,Masahiro Hoshino,Tetsumin Lee,Yoshihisa Kanaji,Masao Yamaguchi,Masahiro Hada,Yohei Sumino,Hiroaki Ohya,Yoshinori Kanno,Hidenori Hirano,Tomoki Horie,Takayuki Niida,Junji Matsuda,Tomoyuki Umemoto,Taro Sasaoka,Yu Hatano,Tomoyo Sugiyama,Tetsuo Sasano,Tsunekazu Kakuta

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2020）

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摘要

•Plaque erosion is the second major pathological substrate of acute coronary syndrome (ACS).•Plaque erosion is characterized with intact fibrous cap on optical coherence tomography.•Patients with low low-density lipoprotein cholesterol showed more intact fibrous cap at the culprit lesion.•Intact fibrous cap plaque might be the major cause of ACS after failed primary prevention.

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关键词

Acute myocardial infarction,Optical coherence tomography,Plaque rupture,Cholesterol

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