Synthesis, Characterization, and Dynamic Behavior of Well-defined Dithiomaleimide-functionalized Maltodextrins
LETTERS IN ORGANIC CHEMISTRY(2020)
摘要
Maltodextrins have an increasing number of biomedical and industrial applications due to their attractive physicochemical properties such as biodegradability and biocompatibility. Herein, we describe the development of a synthetic pathway and characterization of thiol-responsive maltodextrin conjugates with dithiomaleimide linkages. F-19 NMR studies were also conducted to demonstrate the exchange dynamics of the dithiomaleimide-functionalized sugar end groups.
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关键词
Maltodextrin,dibromomaleimide,click chemistry,thiol release,sugar conjugates,F-19 NMR
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