Pituitary adenylate cyclase-activating polypeptide (PACAP): Differential effects on neonatal vs adult megakaryocytopoiesis

Sanjeev Raghuwanshi,Durga Shankar Sharma,Ravinder Kandi,Narasaiah Kovuru,Swati Dahariya,Syed Shahid Musvi,Anuradha Chimata Venkatakrishnan,Adithya Pallepati,Ravi Kumar Gutti

Thrombosis Research（2019）

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摘要

•Human CD34+ cells at different developmental stages were cultured & differentiated.•We examined effects of PACAP on megakaryocytes at different developmental stages.•PACAP is more effective inhibitor of neonatal megakaryocytopoiesis.

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