P98 Responsiveness of the EQ5D5L to pulmonary rehabilitation

Introduction The EQ5D5L, a generic health status measure, is responsive to pulmonary rehabilitation (PR) in those with COPD (1), however responsiveness in other pathologies is not known. As a utility index (UI) it can be used to establish the cost effectiveness of PR programmes, many of which are not uni-pathology. The applicability and outcomes of EQ5D5L in a ‘real life’ multi-pathology PR programme is described. Aim To assess the responsiveness of the EQ5D5L in a UK PR service which includes those with varied respiratory diagnoses. Methods The EQ5D5L UI and visual analogue scale (VAS), Anchor question, COPD Assessment Test (CAT) and either the six-minute or incremental shuttle walk test (6 MWT; ISWT) were completed by patients pre- and post-PR from October 2016 to July 2018. Changes in outcomes are reported as mean ±SD. Paired t-tests were used to test within subject differences and Spearman’s correlation to test for associations. Results 131 patients (mean age 66±16; 76% COPD; FEV 1 60%±22% predicted) completed PR. Following PR, there were significant improvements in CAT (3.1±6.7, p Conclusions These findings show the EQ5D5L is responsive to a ‘real life’ PR programme. The observed improvements are below or at the lower limits of reported minimal important differences (MID) for VAS and UI, 6.5% to 10.1% and 0.037 to 0.109, respectively. 1 This may indicate that the MID differs in those with diagnoses other than COPD. The EQ5D5L may be of use as a PR quality indicator and may provide a novel approach to allow PR services to evaluate their cost-effectiveness. Further work to determine the MID and responsiveness in a mixed population is required. Reference Nolan CM, Longworth L, Lord J, Canavan JL, Jones SE, Kon SS, et al . The EQ-5D-5L health status questionnaire in COPD: validity, responsiveness and minimum important difference. Thorax 2016; 71 (6):493–500.