Phase 2 Study Investigating The Safety, Efficacy, And Surrogate Biomarkers Of Response To 5-Azacitidine (5-Aza) And Entinostat In Advanced Breast Cancer

Roisin M. Connolly,Rachel Catherine Jankowitz,Cynthia A. Zahnow,Zhe Zhang,Michelle A. Rudek,Shannon Slater,Penny Powers,Stacie Jeter,Adam Brufsky,Richard Piekarz,James Gordon Herman,Nita Ahuja,George Somlo,Agustin A. Garcia,Stephen Baylin,Nancy E. Davidson,Vered Stearns

JOURNAL OF CLINICAL ONCOLOGY（2014）

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569 Background: In breast cancer models, combination epigenetic therapy with a DNA methyltransferase inhibitor and a histone deacetylase inhibitor led to re-expression of genes encoding important t...

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advanced breast cancer,breast cancer,surrogate biomarkers

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