Unnatural tripeptide as highly enantioselective organocatalyst for asymmetric aldol reaction of isatins
Tetrahedron Letters(2019)
摘要
•Tripeptides containing d-amino acid were prepared.•Asymmetric Aldol reaction using our tripeptide organocatalyst.•Construction of 3-hydroxyl-2-oxindolesusing with excellent ee.
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关键词
Peptide,Organocatalyst,Aldol reaction,Isatins,Enantioselective
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