Synthesis of acetamides using CO2, methanol, H2 and amines

Herein, we report the synthesis of acetamides from CO2, methanol, H-2 and corresponding amines, which is a new route used to synthesize acetamides. It was found that the Rh catalyst with LiI/LiCl as promoters could effectively catalyze this reaction. Interestingly, no ligand was required and amine substrates played a role in accelerating the reaction.