Mechanical Active Compression-Decompression With Lucas2ad Provide Equivocal P(Et)Co(2) Values To The Standard Lucas2 During Out-Of-Hospital Cardiopulmonary Resuscitation

Introduction: Studies comparing manual active compression-decompression CPR (ACD-CPR) to manual CPR have shown similar survival rates. Recently a new mechanical ACD-CPR device (LUCAS2AD, Jolife AB/Physio-Control, Lund, Sweden) was compared to the standard LUCAS2 device in pigs, documenting improved hemodynamics. In this first clinical study on mechanical ACD-CPR we hypothesized that it would produce better hemodynamic variables than the standard LUCAS2 device (ClinicalTrials.gov NCT02479152). Methods: The trial is a prospective block-randomized unblinded study of out-of-hospital cardiac arrest patients u003e18 years old with anterior-posterior (AP) chest diameter 185-280mm, treated by the physician manned vehicle in Oslo. Inclusion criteria: simultaneous minimum 5 minutes of LUCAS2/LUCAS2AD chest compressions, intubated and side stream pCO2 measurements. Exclusion criteria: traumatic arrest, pregnancy, imprisonment and previous chest surgery. LIFEPAK 15 data was exported via CodeStat 10 (both PhysioControl, R...