The amyloid precursor protein (APP) processing as a biological link between Alzheimer’s disease and cancer

Fernando Galvão,Kamila Castro Grokoski,Bruno Batista da Silva,Marcelo Lazzaron Lamers,Ionara Rodrigues Siqueira

Ageing Research Reviews（2019）

引用 42|浏览18

暂无评分

摘要

•Alzheimer disease seems to have an inverse association with cancer.•Amyloid Precursor Protein processing may be the convergent mechanism of cancer and AD.•The imbalance between non-amyloidogenic and amyloidogenic pathways seems involved.•Non-amyloidogenic pathway is linked to several malignancies.

查看译文

关键词

Alzheimer disease,Cancer,Aging,Amyloid precursor protein,Amyloidogenic pathway,Non- amyloidogenic pathway

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要