“Risk is in the air”: Polycyclic aromatic hydrocarbons, metals and mutagenicity of atmospheric particulate matter in a town of Northern Italy (Respira study)

Donatella Feretti,Roberta Pedrazzani,Elisabetta Ceretti,Mario Dal Grande,Ilaria Zerbini,Gaia Claudia Viviana Viola,Umberto Gelatti,Francesco Donato,Claudia Zani

Mutation Research/Genetic Toxicology and Environmental Mutagenesis（2019）

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摘要

•The finest urban air PM was distributed evenly throughout the town.•Urban air particulate matter induced DNA damage in bacteria, plant and human cells.•Mutagenicity was associated with the finest fraction of PM (PM0.5 and PM0.5-3).•PM0.5 exhibited the highest concentration of PAHs and genotoxic potential.•Metals and semi-metals in PM10 originate from traffic and steel plants.

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关键词

PM mutagenicity,Allium cepa test,Ames test,Comet assay,Diagnostic ratio,PAHs and metals

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